Location History:
- Hockenheim, DE (1976 - 1978)
- Hackenheim, DE (1980)
Company Filing History:
Years Active: 1976-1980
Title: Werner Rothe: Innovator in Pharmaceutical Solutions
Introduction
Werner Rothe is a notable inventor based in Hockenheim, Germany. He has made significant contributions to the field of pharmaceuticals, holding a total of 7 patents. His work focuses on developing innovative solutions that enhance the efficacy and safety of medical treatments.
Latest Patents
Among his latest patents, Rothe has developed an instillation composition that includes an effective amount of at least one sparingly soluble active material. This material is suspended or partly dissolved in an aqueous emulsion containing a swelling agent. The active substances include nitrofurantoin or a quinolone or pyridazine derivative, with a particle size of less than about 10 µm. The composition also contains a polysaccharide derivative as a swelling agent, present in about 0.3 to 3% by weight. Additionally, it incorporates at least one local anesthetic, antiphlogistic substance, emulsifier, buffer, or stabilizer, allowing for unit doses of only 50 ml to contain sufficient active material.
Another significant patent involves stable, physiologically compatible injectable solutions. These solutions comprise an alkali metal salt of canrenoic acid or a mixture of an alkali metal canrenoate and a diuretic. They also include an aqueous, physiologically compatible alkaline buffer with a low buffer capacity, yielding a pH range of 10.2 to 11.2. Examples of suitable buffers are tripotassium phosphate, potassium carbonate, or potassium glycinate.
Career Highlights
Werner Rothe is associated with Boehringer Mannheim GmbH, a company known for its commitment to innovation in the pharmaceutical industry. His work has contributed to the development of advanced medical solutions that address various health challenges.
Collaborations
Throughout his career, Rothe has collaborated with esteemed colleagues such as Helmut Heinemann and Gregor Groppenbacher. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and expertise.
Conclusion
Werner Rothe's contributions to pharmaceutical innovations demonstrate his commitment to improving medical treatments. His patents reflect a deep understanding of the complexities involved in drug formulation and delivery. His work continues to influence the field and enhance patient care.