This inventor holds 3 USPTO granted patents. Top assignee: Eli Lilly and Company. Active years: 1988-1991.
Company Filing History:
Years Active: 1988-1991
Title: Werner M Seidler: Innovator in Pharmaceutical Coatings
Introduction
Werner M Seidler is a notable inventor based in Indianapolis, IN (US). He has made significant contributions to the field of pharmaceutical formulations, holding a total of 3 patents. His work focuses on developing innovative coating technologies that enhance drug delivery systems.
Latest Patents
One of his latest patents is related to film coating formulations. This invention involves aqueous diffusion coating formulations suitable for use on pharmaceutical dosage forms. The formulations comprise an admixture of an insoluble polymer component of a copolymer of ethylacrylate and methylmethacrylate, along with the hydrophilic component, the polysaccharide pullulan. When applied to the substrate of choice, these formulations provide coatings that exhibit good mechanical strength and flexibility.
Another significant patent by Seidler is for a sustained release matrix. This invention provides a matrix composition for sustained drug delivery, which includes an active agent, a hydrophilic polymer, and an enteric polymer. The enteric polymer is impermeable to gastric fluids and aids in retarding drug release in regions of low pH. This allows for lower levels of hydrophilic polymer to be employed. At the pH range of intestinal fluids, this polymer dissolves, increasing the permeability of the dosage form. This approach is particularly useful for sustaining the release of numerous active agents whose solubility declines as the pH increases, a characteristic of weakly basic drugs.
Career Highlights
Werner M Seidler is currently associated with Eli Lilly and Company, where he continues to innovate in the pharmaceutical sector. His work has contributed to advancements in drug delivery systems, making medications more effective and patient-friendly.
Collaborations
Throughout his career, Seidler has collaborated with notable colleagues, including Peter L Oren and Ray F Childers. These collaborations have further enriched his research and development efforts in the pharmaceutical field.
Conclusion
Werner M Seidler is a distinguished inventor whose work in pharmaceutical coatings has led to significant advancements in drug delivery systems. His innovative patents reflect his commitment to improving patient care through effective medication formulations.
