Wenqi Ye

Title: Innovations of Wenqi Ye in Enzyme Engineering

Introduction

Wenqi Ye is a notable inventor based in Wuxi, China. He has made significant contributions to the field of enzyme engineering, particularly through his innovative patent work. His research focuses on enhancing enzyme functionality for industrial applications.

Latest Patents

Wenqi Ye holds a patent for an L-aspartate alpha-decarboxylase mutant and its applications. This patent discloses a mutant enzyme where lysine at position 221 is mutated to arginine and glycine at position 369 is mutated to alanine. The resulting mutant enzymes exhibit improved temperature tolerance, making them advantageous for industrial production. The K221R and G369A recombinant strains undergo high-density fermentation using sodium L-aspartate as a substrate, facilitating a whole cell catalytic reaction to produce β-alanine. This method is noted for its safety and cleanliness, avoiding environmental pollution, and offers a simple and convenient operation compared to pure enzyme catalysis. The yield of β-alanine reaches 91% and 90%, with concentrations of 162.15 g/L and 160.42 g/L, respectively.

Career Highlights

Wenqi Ye is affiliated with Jiangnan University, where he continues to advance his research in enzyme engineering. His work has garnered attention for its practical applications in industrial processes.

Collaborations

Wenqi Ye collaborates with esteemed colleagues, including Zhemin Zhou and Zhongmei Liu, who contribute to his research endeavors.

Conclusion

Wenqi Ye's innovative work in enzyme engineering, particularly through his patented L-aspartate alpha-decarboxylase mutant, showcases his commitment to advancing industrial biotechnology. His contributions are paving the way for safer and more efficient production methods.