Wenli Li

Title: Biography of Inventor Wenli Li

Introduction

Wenli Li is a prominent inventor based in Shandong, China, known for his significant contributions to the field of enzymology and drug development. With a total of three patents to his name, he has made remarkable advancements in the application of enzymes for pharmaceutical purposes.

Latest Patents

Wenli Li's latest patents include:

1. **Enzyme with acyl transfer function and application thereof** - This invention describes an enzyme with an acyl transfer function that has an amino acid sequence identical to a specific SEQ ID NO. It is capable of acylation modification for macrolactins, filipins macrolides, chloramphenicol, and glycosylated piericidin A. The application of this acyltransferase binds an acyl group of an acyl donor to macrolide compounds, enhancing their pharmacological activity and bioavailability while reducing toxicity and side effects.

2. **Method for assembling prenyl groups onto cyclic dipeptides** - This patent introduces a novel PSL family prenyltransferase with relaxed substrate specificity, allowing it to utilize various cyclic dipeptides and prenyl donors to produce terpenylated diketopiperazines. The enzyme catalyzes the formation of these compounds, providing a new strategy for drug development in this area.

Career Highlights

Wenli Li has worked at notable institutions, including