Company Filing History:
Years Active: 1994-2004
Title: Innovations of Wen Y Chen in Growth Hormone Antagonists
Introduction
Wen Y Chen is a prominent inventor based in Athens, OH (US), known for her significant contributions to the field of biotechnology. With a total of 5 patents, her work primarily focuses on the development of DNA molecules that encode growth hormone antagonists. These innovations have the potential to revolutionize treatments for various growth-related disorders.
Latest Patents
One of her latest patents involves DNA encoding growth hormone antagonists. This invention relates to DNA molecules that encode antagonists of vertebrate growth hormones, specifically through mutations of the amino acid corresponding to Glu-119 in bovine growth hormone. The DNA molecules can be utilized to express these antagonists in cell cultures or directly in patients, thereby inhibiting growth hormone activity. Another significant patent addresses methods for treating acromegaly and gigantism using growth hormone antagonists. This invention describes antagonists obtained by mutating the third alpha helix of growth hormones, which can be administered to animals or expressed in transgenic animals. The invention also outlines methods for treating various diseases, including cancer and diabetes, by administering effective amounts of growth hormone antagonists.
Career Highlights
Wen Y Chen has had a distinguished career, working at notable institutions such as Ohio University and the Edison Biotechnology Institute. Her research has significantly advanced the understanding of growth hormone functions and their implications in medical treatments.
Collaborations
Throughout her career, she has collaborated with esteemed colleagues, including John J Kopchick, enhancing the impact of her research through shared expertise and innovation.
Conclusion
Wen Y Chen's contributions to the field of biotechnology, particularly in the development of growth hormone antagonists, showcase her innovative spirit and dedication to advancing medical science. Her work continues to pave the way for new treatment options for patients suffering from growth-related disorders.