The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2004
Filed:
Jun. 07, 1995
Applicant:
Inventors:
John J. Kopchick, Athens, OH (US);
Wen Y. Chen, Athens, OH (US);
Assignee:
Ohio University/Edison Biotechnology Institute, Athens, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/21 ; C12N 5/10 ; C12N 1/518 ; C12N 1/563 ;
U.S. Cl.
CPC ...
C12N 1/21 ; C12N 5/10 ; C12N 1/518 ; C12N 1/563 ;
Abstract
The present invention relates to DNA molecules which encode antagonists of vertebrate growth hormones obtained by mutation of at least the amino acid corresponding to Glu-119 in bovine growth hormone. The DNA molecules may be used to express the antagonists, either in cell culture, or in the cells of the patient of interest. The antagonist so expressed may be used to inhibit GH activity in a subject.