Weijie Zhao

Title: Weijie Zhao and Advances in Porous Resins for Oligonucleotide Synthesis.

Introduction

Weijie Zhao is an inventor associated with Shaanxi, China, and Sunresin New Materials Co. Ltd. His work includes a porous resin designed for use as a solid-phase synthesis carrier, with potential to improve the yield and purity of oligonucleotides. Zhao is associated with 1 patent.

Latest Patents

Zhao’s patent, “Porous Resin Used to Solid Phase Synthesis and Preparation Method Therefor,” describes a porous resin bearing amino or hydroxyl functional groups and a method for preparing it. The process uses an olefin compound containing two cyano groups as a modified monomer and a high internal phase emulsion as a pore-forming agent during suspension polymerization. The resulting resin is then functionalized to introduce amino or hydroxyl groups.

According to the patent description, the modified monomer helps distribute functional groups more uniformly and brings the resin’s swelling behavior closer across different solvents. The emulsion-based pore-forming approach also produces a narrower pore-size distribution. As a solid-phase synthesis carrier, the resin is intended to support oligonucleotide preparation and help improve product yield and purity.

Career Highlights

Zhao’s disclosed invention focuses on materials and preparation methods for solid-phase synthesis. Its design combines controlled pore formation with functionalization to address carrier properties relevant to oligonucleotide production.

Collaborations

Zhao is associated with Sunresin New Materials Co. Ltd. His listed coworkers include Chaoyang Wang and Cheng Zhang.

Conclusion

Weijie Zhao’s patent presents a porous resin carrier and preparation method aimed at more consistent material properties and improved oligonucleotide synthesis outcomes.