Houston, TX, United States of America

Wei Ye




Average Co-Inventor Count = 4.0

ph-index = 1

Forward Citations = 3(Granted Patents)


Company Filing History:


Years Active: 2017-2020

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3 patents (USPTO):Explore Patents

Title: Innovations by Inventor Wei Ye

Introduction

Wei Ye, an accomplished inventor based in Houston, TX, has made significant contributions to the field of chemotherapeutic compounds. With three patents to his name, he focuses on developing innovative antiviral agents that showcase promising antiviral activity against various diseases.

Latest Patents

Wei Ye's latest patents include the development of enantiomers of the 1',6′-isomer of neplanocin A. The patents disclose these enantiomers, along with novel synthetic methods, including the synthesis of a substituted cyclopentane epoxide. He has also worked on the enantiomers of carbocyclic nucleoside analogs of 3-deazaneplanocin, yielding D- and L-like 1',6′-iso-3-deazaneplanocin. These small molecule chemotherapeutic compounds are beneficial in providing DNA and RNA antiviral activity, with demonstrated effectiveness against various viruses, such as human cytomegalovirus, measles, Ebola, norovirus, dengue, vaccinia, and hepatitis B virus (HBV). Furthermore, the compounds display reduced S-adenosylhomocysteine hydrolase inhibitory effects, resulting in improved toxicity profiles compared to neplanocin, thus enhancing their prophylactic and therapeutic antiviral efficacy.

Career Highlights

Wei Ye is currently associated with Auburn University, where he engages in cutting-edge research aimed at developing new antiviral therapies. His innovative approach and commitment to research have enabled him to create impactful inventions that contribute to the broader field of medicine and public health.

Collaborations

Throughout his career, Wei Ye has collaborated with notable coworkers, including Stewart W. Schneller and Chong Liu. These partnerships have allowed him to leverage diverse expertise, fostering an environment of innovation and creativity in the development of new therapeutic agents.

Conclusion

Wei Ye's contributions to the field of antiviral research highlight the importance of innovation in addressing global health challenges. His patents represent significant advancements in the development of effective treatments against various viral infections, underscoring his role as a prominent inventor in the scientific community.

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