Wei Yan

Title: Wei Yan: Innovator in Pharmaceutical Chemistry

Introduction

Wei Yan is a prominent inventor based in Taizhou, China, known for his significant contributions to pharmaceutical chemistry. He holds 2 patents that focus on innovative methods for drug preparation, showcasing his expertise in enzymatic processes.

Latest Patents

One of Wei Yan's latest patents is titled "Method for enzymatic preparation of fludarabine phosphate." This method involves the reaction of fludarabine with a high-energy phosphate compound under the action of deoxyribonucleic acid kinase. The process effectively addresses technical problems present in existing methods by employing an enzymatic approach. By adding acetate kinase, the method reduces the usage of high-energy phosphate compounds, thereby minimizing by-product generation and enhancing purification steps in industrial production. The process is environmentally friendly, cost-effective, and yields high purity products.

Another notable patent is "Method for preparing epirubicin and intermediate thereof." This invention outlines a preparation method that includes several steps, such as reacting tert-Butyldimethylsilyl chloride with N-trifluoroacetyl adriamycin to obtain a specific compound. The method is characterized by its low cost, fewer reaction steps, high yield, and avoidance of pollution typically associated with conventional bromination reactions.

Career Highlights

Wei Yan is currently associated with Zhejiang Hisun Pharmaceutical Co., Ltd., where he applies his innovative techniques to advance pharmaceutical manufacturing. His work has significantly impacted the efficiency and sustainability of drug production processes.

Collaborations

Wei Yan collaborates with notable colleagues, including Dejin Fu and Yong Yang, who contribute to his research and development efforts in the pharmaceutical field.

Conclusion

Wei Yan's innovative approaches in pharmaceutical chemistry, particularly in the preparation of fludarabine phosphate and epirubicin, highlight his role as a key inventor in the industry. His contributions not only enhance production efficiency but also promote environmentally friendly practices in drug manufacturing.