Company Filing History:
4 out of 46 
1 out of 24 
1 out of 6 Years Active: 1993-2001
Title: Innovations by Wei-Tao Tian: Pioneering Monoclonal Antibody Research
Introduction
Wei-Tao Tian, an accomplished inventor based in Allston, MA, has made significant contributions to the field of immunology through his groundbreaking inventions. With a total of six patents to his name, Tian's innovations center around monoclonal antibodies and their applications in diagnosis and therapy, enhancing our understanding of the immune system.
Latest Patents
One of Wei-Tao Tian's notable patents is titled "Monoclonal antibodies reactive with defined regions of the T cell antigen receptor." This invention focuses on monoclonal antibodies that recognize specific regions of the T-cell receptor (TCR). In a specific embodiment, it provides antibodies that act upon the constant region of the alpha chain of the TCR. The invention features two unique monoclonal antibodies, labeled αF1 and αF2, which react with distinct epitopes on the alpha monomer's framework region. Furthermore, the patent covers monoclonal antibodies targeting variable regions of the beta chain of the TCR, specifically W112 and 2D1, which respond to variable regions Vβ5.3 and Vβ8.1. Additionally, the invention includes monoclonal antibody δTCS1, isotype IgG2a, which is directed towards a variable region of the delta chain of the TCR. These antibodies serve critical roles in the diagnosis and treatment of diseases and are invaluable tools for studying immune responses.
Career Highlights
Throughout his career, Wei-Tao Tian has worked with prominent companies in the biotech field, including Astra AB and T Cell Sciences, Inc. His professional journey reflects a dedication to advancing medical research and therapeutic solutions through innovation.
Collaborations
In pursuit of his inventions, Tian has collaborated with esteemed colleagues, including Charles William Rittershaus and Patrick C Kung. Their joint efforts have contributed to the successful development and commercialization of innovative monoclonal antibody therapies.
Conclusion
Wei-Tao Tian's contributions to the field of immunology through his patented inventions have paved the way for enhanced diagnostic and therapeutic methodologies. His work in developing monoclonal antibodies reactive with various regions of the T-cell receptor is a testament to his commitment to innovation and advancement in medical science. With ongoing research and collaborative efforts, Tian continues to be a vital figure in the landscape of modern immunological research.
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