Wei-Shuo Lo

Title: Innovations of Wei-Shuo Lo in Pharmaceutical Chemistry

Introduction

Wei-Shuo Lo is a notable inventor based in Tainan, Taiwan. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the synthesis of important drug compounds. With a total of 4 patents to his name, his work has advanced the methods used in drug preparation and formulation.

Latest Patents

One of Wei-Shuo Lo's latest patents is titled "Process for preparing ibrutinib and its intermediates." This invention provides efficient, economical, and improved methods for synthesizing ibrutinib and its intermediates. The unique biphasic acylation reaction system described in the patent allows for easy separation of ibrutinib from the reaction mixture without additional extraction and wash steps. The isolated ibrutinib formed using these methods can be useful in preparing an amorphous form of ibrutinib. In some embodiments, the isolated ibrutinib produced is a homogeneous solution of ibrutinib and DMSO, which may be directly used in the formation of the amorphous polymorph. Additionally, the isolated solid ibrutinib can also be utilized in the formation of amorphous ibrutinib.

Another significant patent by Wei-Shuo Lo is "Forms of apremilast and the process of making the same." This invention provides novel crystalline forms of apremilast hemitoluene solvate, apremilast hydrate, and apremilast anhydrate, along with an amorphous form of apremilast. The processes for preparing these forms are also detailed in the patent, showcasing his innovative approach to drug formulation.

Career Highlights

Wei-Shuo Lo has worked with reputable companies in the pharmaceutical industry, including Scinopharm Taiwan Ltd. and Scintopharm Taiwan Ltd. His experience in these organizations has contributed to his expertise in drug development and patenting.

Collaborations

Some of his notable coworkers include YuanChang Huang and Ying-Tzu Lin. Their collaborative efforts have likely played a role in the successful development of his patented inventions.

Conclusion

Wei-Shuo Lo's contributions to pharmaceutical chemistry through his innovative patents demonstrate his commitment to advancing drug synthesis and formulation techniques. His work continues to impact the field positively, paving the way for future advancements in medication development.