This inventor holds 3 USPTO granted patents and 7 published patent applications. Top assignees: Harvard College, The Broad Institute, Inc.. Active years: 2022-2026.
Company Filing History:
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Years Active: 2022-2026
Title: Innovations by Wei Hsi Yeh in Gene Editing Technologies
Introduction
Wei Hsi Yeh is an accomplished inventor based in Cambridge, MA. He has made significant contributions to the field of gene editing, particularly through his innovative approaches to delivering nucleobase editors. His work is pivotal in advancing the capabilities of genetic engineering.
Latest Patents
Wei Hsi Yeh holds a patent for "AAV delivery of nucleobase editors." This patent outlines methods for delivering 'split' Cas9 protein or nucleobase editors into cells using recombinant adeno-associated virus (rAAV). The invention details how the Cas9 protein or nucleobase editor is divided into two sections, each fused with parts of an intein system. Upon co-expression, these sections are ligated together through intein-mediated protein splicing. The patent also includes recombinant AAV vectors and particles designed for the effective delivery of these components.
Career Highlights
Wei Hsi Yeh is affiliated with Harvard College, where he continues to push the boundaries of research in genetic engineering. His work has garnered attention for its potential applications in various fields, including medicine and biotechnology.
Collaborations
He has collaborated with notable researchers such as David R Liu and Jonathan Ma Levy, contributing to a rich environment of innovation and discovery.
Conclusion
Wei Hsi Yeh's contributions to gene editing through his innovative patent demonstrate his commitment to advancing scientific knowledge and technology. His work is a testament to the potential of genetic engineering in transforming various industries.