Wei Cao

Title: Innovations by Wei Cao in Drug Concentration Measurement

Introduction

Wei Cao is an accomplished inventor based in Centereach, NY (US). He has made significant contributions to the field of pharmacology, particularly in the measurement of drug concentrations in human plasma. His innovative methods have the potential to enhance the efficacy of protease inhibitors used in antiviral therapies.

Latest Patents

Wei Cao holds a patent for "Methods for determining plasma free drug concentration by direct measurement of binding affinity of protease inhibitors to plasma proteins." This patent outlines methods for isothermal titration calorimetry analysis of the binding affinity of protease inhibitors to plasma proteins. The invention quantitatively calculates free drug concentrations of protease inhibitors in human plasma. It also provides a method to determine therapeutic amounts and dosage regimens. Furthermore, the invention evaluates the effect of plasma proteins on the antiviral activity (EC50 values) of protease inhibitors based on their binding affinities. Additionally, it offers a method to assess the in vivo anti-HIV efficacy of protease inhibitors in human plasma.

Career Highlights

Wei Cao is currently associated with Tibotec Pharmaceuticals Ltd., where he applies his expertise in drug development and pharmacology. His work focuses on improving treatment options for patients through innovative research and development.

Collaborations

Wei Cao has collaborated with notable colleagues, including Dong Xie and John W. Erickson. Their combined efforts contribute to advancements in the field of antiviral therapies.

Conclusion

Wei Cao's innovative methods for measuring drug concentrations represent a significant advancement in pharmacology. His contributions have the potential to improve therapeutic outcomes for patients using protease inhibitors.