Somerville, MA, United States of America

Wei C Goh


Average Co-Inventor Count = 2.6

ph-index = 4

Forward Citations = 56(Granted Patents)


Location History:

  • Stanford, CA (US) (1997)
  • Somerville, MA (US) (1990 - 1998)

Company Filing History:


Years Active: 1990-1998

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5 patents (USPTO):Explore Patents

Title: Innovations and Contributions of Wei C Goh

Introduction

Wei C Goh is a prominent inventor based in Somerville, MA, known for his significant contributions to the field of biotechnology. He has been instrumental in developing innovative assay methods that have implications for HIV research and treatment. With a total of five patents to his name, Goh's work continues to influence the scientific community.

Latest Patents

Wei C Goh's latest patents include groundbreaking methods for assay techniques involving tat cell lines. One of his notable inventions focuses on assays screened for compounds that inhibit tat transactivation of the HIV (HTLV-III) LTR. This assay involves transfecting a cell line containing the tat gene with a vector that includes a gene controlled by the HIV-1 LTR. The process includes adding the compound to be screened and determining its effect by measuring the expression of the gene under the control of the HIV LTR. Additionally, Goh has developed cis-acting repression sequences and cis-acting antirepression sequences. These sequences can provide an inhibitory effect on gene expression when placed downstream of the gene in its untranslated message. They also correspond to a sufficient number of nucleotides from the HIV-I, HIV-2, STLV-3, or HTLV-IV genomes, which are essential for the repression or anti-repression effects.

Career Highlights

Wei C Goh is currently affiliated with the Dana-Farber Cancer Institute, where he continues to advance his research in cancer and viral diseases. His work has garnered attention for its potential applications in therapeutic strategies against HIV and other related conditions.

Collaborations

Throughout his career, Goh has collaborated with notable figures in the field, including William A Haseltine and Craig A Rosen. These collaborations have further enriched his research and expanded the impact of his inventions.

Conclusion

Wei C Goh's innovative contributions to biotechnology, particularly in the realm of HIV research, highlight his role as a leading inventor. His patents and ongoing work at the Dana-Farber Cancer Institute continue to pave the way for advancements in medical science.

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