Wayne R Gombotz

Title: The Innovative Journey of Wayne R. Gombotz

Introduction

Wayne R. Gombotz, an accomplished inventor based in Lexington, Massachusetts, has made significant contributions to the field of biologically active molecules through his innovative patents. With a total of two patents to his name, he has developed groundbreaking processes that enhance the delivery and effectiveness of biologically active agents.

Latest Patents

Wayne Gombotz's most recent patents focus on advanced methods for producing small particles of biologically active molecules. His first patent describes a process wherein small diameter particles, ranging from approximately 10 to 90 micrometers, are created by atomizing solutions through a nozzle into very cold liquefied gases. This immediate freezing results in frozen particles that, when lyophilized, create porous structures. These particles retain more than 70% to 95% of their initial biological activity after being processed to achieve diameters as small as 0.1 to 10 micrometers.

His second patent outlines a method for preparing controlled release microspheres at very cold temperatures. This innovative process freezes a mixture of polymers and biologically active agents to produce microspheres that maintain a high retention of biological activity. The method involves atomizing these mixtures into a non-solvent environment, resulting in hardened microspheres that effectively deliver their active contents.

Career Highlights

Throughout his career, Wayne has been associated with prominent companies in the biotechnology sector, including Enzytech, Ltd. and Alkermes Controlled Therapeutics, Inc. His work in these organizations has positioned him as a key figure in the development of drug delivery systems and solutions that enhance the stability and efficacy of various biological agents.

Collaborations

Wayne has collaborated with notable colleagues such as Michael S. Healy and Larry Richard Brown, contributing to projects that leverage their combined expertise in biochemistry and materials science. These collaborations have led to innovative outcomes that are impactful in the medical and pharmaceutical industries.

Conclusion

Wayne R. Gombotz stands as a distinguished inventor whose work in the field of biologically active molecules continues to influence advancements in drug delivery systems. His patents not only demonstrate a deep understanding of chemical processes but also highlight his commitment to enhancing the efficacy of therapeutic agents for better health outcomes.