San Diego, CA, United States of America

Wayne D Kornreich


Average Co-Inventor Count = 4.3

ph-index = 5

Forward Citations = 84(Granted Patents)


Company Filing History:


Years Active: 1986-1996

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6 patents (USPTO):Explore Patents

Title: Wayne D. Kornreich: Innovator in CRF Antagonists

Introduction

Wayne D. Kornreich is a notable inventor based in San Diego, California. He has made significant contributions to the field of biological studies, particularly in the development of CRF antagonists. With a total of 6 patents to his name, Kornreich's work has had a substantial impact on the understanding and treatment of various physiological conditions.

Latest Patents

Kornreich's latest patents focus on CRF analogs, which are derived from human corticotropin-releasing factor (hCRF), ovine corticotropin-releasing factor (oCRF), and alpha-helical CRF. These analogs are designed to be administered to achieve a significant elevation of ACTH, β-endorphin, β-lipotropin, and corticosterone levels. The specific formula for these analogs includes a complex sequence of amino acids, allowing for the creation of particularly potent CRF antagonists by shortening the N-terminus by 11 residues.

Career Highlights

Kornreich is affiliated with the Salk Institute for Biological Studies, where he has conducted extensive research in his field. His innovative work has contributed to advancements in understanding the mechanisms of stress and hormonal regulation.

Collaborations

Throughout his career, Kornreich has collaborated with esteemed colleagues such as Jean E. Rivier and Wylie W. Vale, Jr. These partnerships have further enriched his research and expanded the impact of his inventions.

Conclusion

Wayne D. Kornreich's contributions to the field of biological studies through his patents on CRF antagonists highlight his role as a significant innovator. His work continues to influence research and treatment strategies in the realm of hormonal regulation.

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