This inventor holds 1 USPTO granted patent. Top assignees: Jiangnan University, Yangzhou Rixing Bio-Tech Co., Ltd. Active years: 2019.
Company Filing History:
1 out of 560 
1 out of 1 Years Active: 2019
Title: Wanhong Zhang: Innovator in Glucosamine Synthase Technology
Introduction
Wanhong Zhang is a notable inventor based in Gaoyou, Japan. He has made significant contributions to the field of biotechnology, particularly in the development of glucosamine synthase mutants. His innovative work has led to advancements in the efficiency of enzyme-substrate interactions.
Latest Patents
Wanhong Zhang holds a patent titled "Directed modification of glucosamine synthase mutant and application thereof." This invention discloses a directionally modified glucosamine synthase mutant and its application. The amino acid sequence of the glucosamine synthase mutant is detailed in sequence list SEQ ID No. 1, while the nucleotide sequence is provided in sequence list SEQ ID No. 2. The genetic engineering bacteria of glucosamine synthase has been successfully constructed. To enhance the tolerance of recombinant bacteria against glucosamine, the glucosamine synthase is directionally modified. A glucosamine synthase mutant is selected from the mutant library through a high-throughput screening method. The amino acid changes in the mutant induce spatial conformational changes in the enzyme, thereby enlarging the region where the enzyme and substrate combine. Consequently, the combination efficiency of the enzyme and substrate is increased. The glucosamine synthase of this invention offers various advantages, such as being rich in raw material of glucose and allowing for convenient subsequent extraction. Wanhong Zhang has 1 patent to his name.
Career Highlights
Throughout his career, Wanhong Zhang has worked with reputable organizations, including Yangzhou Rixing Bio-Tech Co., Ltd and Jiangnan University. His experience in these institutions has contributed to his expertise in biotechnology and enzyme engineering.
Collaborations
Wanhong Zhang has collaborated with notable colleagues, including Jinsong Shi and Heng Li. Their combined efforts have furthered research and development in the field of glucosamine synthase technology.
Conclusion
Wanhong Zhang's innovative work in glucosamine synthase technology exemplifies the impact of biotechnology on enzyme efficiency. His contributions continue to influence advancements in the field, showcasing the importance of research and collaboration in driving innovation.