Location History:
- Proteos, SG (2015 - 2018)
- Singapore, SG (2010 - 2023)
Company Filing History:
6 out of 1,473 
2 out of 805 
1 out of 18 
Years Active: 2010-2023
Title: Walter Hunziker: Innovator in Heart Regeneration and Vitreous Substitute Materials
Introduction
Walter Hunziker is a prominent inventor based in Singapore, known for his significant contributions to medical technology. He holds a total of six patents, focusing on innovative methods for treating heart diseases and developing materials suitable for use as vitreous substitutes.
Latest Patents
One of Hunziker's latest patents is titled "Modulation of TJP1 expression to regulate regeneration of heart cells." This invention presents a method for treating heart disease, particularly acute myocardial infarction (AMI). The method involves administering a Tjp1 inhibitor to promote cardiomyocyte proliferation. Additionally, the invention includes the use of Tjp1 inhibitors in the manufacture of medicaments for heart diseases, patches, and nucleic acids encoding Tjp1 inhibitors. In a specific embodiment, the Tjp1 inhibitor is a nucleic acid, such as siRNA or shRNA of Tjp1. The invention also explores the administration of Tjp1 inhibitors in combination with Neuregulin-1 (NRG1), Fibroblast growth factor (FGF), Vascular endothelial growth factor (VEGF), or Follistatin-like 1 (Fst1), delivered via an adeno-associated virus of serotype 9 (AAV 9).
Another notable patent is related to "Material suitable for use as a vitreous substitute and related methods." This invention describes a material comprising a multi-block thermogelling polymer, which includes hydrophilic, thermosensitive, and hydrophobic polymer blocks. These blocks are chemically coupled through various linkages, making the material suitable for use as a vitreous substitute. The patent also outlines a method for preparing this material and a synthetic vitreous humor or part thereof that incorporates it.
Career Highlights
Walter Hunziker has worked with esteemed organizations such as the Agency for Science, Technology and Research and the National University of Singapore. His work in these institutions has significantly contributed to advancements in medical research and technology.
Collaborations
Hunziker has collaborated with notable colleagues, including Pascal Beguin and M Zakir Hossain, further enhancing the impact of his innovative work.
Conclusion
Walter Hunziker's contributions to the fields of heart regeneration and vitreous substitute materials highlight his role as a leading inventor. His innovative patents and collaborations continue to
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