Wade E Bolton

Title: The Innovative Contributions of Wade E Bolton

Introduction

Wade E Bolton is a notable inventor based in Davie, FL (US), recognized for his significant contributions to the field of biomedical technology. With a total of 4 patents, Bolton has developed innovative methods that enhance the understanding and analysis of cellular processes.

Latest Patents

Bolton's latest patents include a method for distinguishing viable, early apoptotic, late apoptotic, and necrotic cells utilizing multi-color immunofluorescence. This invention provides a crucial tool for researchers in identifying different states of cell viability. Another significant patent is a method of analyzing tumor cell DNA content through tumor cell enrichment. This invention allows for the enrichment of tumor cells in a sample and the determination of DNA ploidy and proliferative index, utilizing a pan-leukocyte monoclonal antibody conjugated to a separable substrate. The method enhances the accuracy of tumor analysis by employing dual color flow cytometry to identify cells with abnormal DNA content.

Career Highlights

Throughout his career, Wade E Bolton has worked with prominent companies such as Coulter Corporation and Coulter International Corp. His experience in these organizations has contributed to his expertise in the field of cellular analysis and immunology.

Collaborations

Bolton has collaborated with notable individuals in his field, including Olavi Siiman and Norma Sue Kenyon. These partnerships have likely enriched his research and development efforts.

Conclusion

Wade E Bolton's innovative patents and career achievements highlight his significant impact on biomedical technology. His work continues to influence the understanding of cellular processes and tumor analysis.