Company Filing History:
Years Active: 2010-2013
Title: Innovations of Wade Aumiller in Catalysis
Introduction
Wade Aumiller is a notable inventor based in Durham, NC (US), recognized for his contributions to the field of catalysis. He holds three patents that showcase his innovative approaches to stereoselective cyclopropanation using ruthenium catalysts. His work has significant implications in organic chemistry and pharmaceutical applications.
Latest Patents
Aumiller's latest patents focus on the development of chiral ruthenium (II) catalysts for use in stereoselective cyclopropanations. These catalysts comprise salen and alkenyl ligands, which are essential for achieving high stereoselectivity in cyclopropanation reactions. The chiral ruthenium catalyst is prepared in situ by combining an alkenyl ligand, a deprotonated chiral salen ligand, and a ruthenium (II) metal. A preferred catalyst is created by combining 2,3-dihydro-4-venylbenzofuran, deprotonated 1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butyl-salicylidene), and RuCl(p-cymene).
Career Highlights
Wade Aumiller is currently employed at Vanda Pharmaceuticals Inc., where he continues to advance his research in catalysis. His work has contributed to the development of new methodologies that enhance the efficiency and selectivity of chemical reactions.
Collaborations
Aumiller has collaborated with notable colleagues, including David Eugene Pereira and Raymond Dagger, to further his research and innovations in the field of catalysis.
Conclusion
Wade Aumiller's innovative work in the development of chiral ruthenium catalysts has made a significant impact in the field of organic chemistry. His contributions continue to influence advancements in stereoselective reactions and pharmaceutical applications.