W Gregory Cox

Title: W Gregory Cox: Innovator in Nucleic Acid Detection

Introduction

W Gregory Cox is a notable inventor based in Eugene, OR (US). He has made significant contributions to the field of molecular biology, particularly in the detection of immobilized nucleic acids. His innovative methods utilize unsymmetrical cyanine dyes, which are derivatives of thiazole orange, to enhance the detection process.

Latest Patents

W Gregory Cox holds 1 patent for his invention titled "Detection of immobilized nucleic acid." This patent outlines methods for determining the presence of immobilized nucleic acid using non-genotoxic compounds. The process involves immobilizing nucleic acid, whether single or double-stranded DNA or RNA, on a solid or semi-solid support. The immobilized nucleic acid is then contacted with an unsymmetrical cyanine dye compound and illuminated with an appropriate wavelength to ascertain the presence of the nucleic acid. This method represents a significant improvement over traditional techniques that utilize ethidium bromide, as it retains the advantages of ease of use and low cost while eliminating the need for special handling and waste procedures.

Career Highlights

W Gregory Cox is associated with Life Technologies Corporation, where he has contributed to advancements in biotechnology. His work focuses on developing innovative solutions for nucleic acid detection, which are crucial for various applications in research and diagnostics.

Collaborations

Throughout his career, W Gregory Cox has collaborated with esteemed colleagues, including Matthew Paul Beaudet and Stephen T Yue. These collaborations have further enriched his research and development efforts in the field.

Conclusion

W Gregory Cox's contributions to the detection of immobilized nucleic acids exemplify the importance of innovation in biotechnology. His patented methods not only improve detection accuracy but also enhance safety in laboratory practices.