Company Filing History:
Years Active: 1999-2000
Title: W Ernest Lyons: Innovator in Neural Regeneration
Introduction
W Ernest Lyons is a notable inventor based in Columbia, MD (US), recognized for his contributions to the field of neural regeneration. He holds 2 patents that focus on stimulating nerve growth through innovative methods involving immunophilins.
Latest Patents
His latest patents include groundbreaking work on stimulating nerve growth with immunophilins. Immunophilin ligands act by binding to receptor proteins, immunophilins, which can regulate the Ca²⁺ dependent phosphatase, calcineurin, and the Ca²⁺ release channel, the ryanodine receptor. These ligands have been discovered to enhance neurite outgrowth in neuronal cell systems by increasing sensitivity to neurotrophic factors. The effects of the immunophilin ligands are detected at subnanomolar concentrations, indicating their therapeutic application in diseases involving neural degeneration.
Career Highlights
W Ernest Lyons is affiliated with The Johns Hopkins University, where he continues to advance research in neural regeneration. His work has significant implications for understanding and treating neural degeneration.
Collaborations
He has collaborated with esteemed colleagues such as Edwin B George and Ted M Dawson, contributing to a rich environment of innovation and research.
Conclusion
W Ernest Lyons stands out as a key figure in the field of neural regeneration, with his innovative patents paving the way for future therapeutic applications. His work exemplifies the intersection of science and innovation, aiming to improve the lives of those affected by neural degeneration.