Company Filing History:
Years Active: 2000
Title: Vladimir Volloch: Innovator in Hsp72 Induction
Introduction
Vladimir Volloch is a notable inventor based in Brookline, MA (US). He has made significant contributions to the field of cellular biology, particularly in the induction of Hsp72, a heat shock protein that plays a crucial role in cellular stress responses.
Latest Patents
Vladimir Volloch holds a patent for a method of inducing Hsp72 production in a cell. The patent describes a process that involves transiently contacting a cell with a proteasome inhibitor in an amount sufficient to induce Hsp72 production. This method is designed to elevate Hsp72 levels to suppress stress-activated kinase activity, which is particularly relevant for stress-activated kinases such as JNK and p38. The applications of this method extend both in vitro and in vivo, including specific applications for aged cells. Additionally, the patent outlines a therapeutic method for treating pathologies associated with apoptosis and inflammation by administering a proteasome inhibitor to induce Hsp72 production, especially in aged individuals.
Career Highlights
Throughout his career, Vladimir Volloch has focused on innovative approaches to cellular stress responses. His work has implications for treating various stress-induced pathologies, including ischemia, which highlights the therapeutic potential of his inventions.
Collaborations
Vladimir has collaborated with notable colleagues such as Michael Sherman and Anatoli Meriin, contributing to advancements in the understanding of Hsp72 and its applications.
Conclusion
Vladimir Volloch's innovative work in Hsp72 induction represents a significant advancement in cellular biology and therapeutic applications. His contributions continue to influence the field and offer potential solutions for stress-related health issues.