This inventor holds 2 USPTO granted patents and 1 published patent application. Top assignees: Innovative Biologics, Inc., University of Virginia Patent Foundation. Active years: 2001-2010.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
1 out of 1 
1 out of 1,044 
Years Active: 2001-2010
Title: Innovations of Vladimir Karginov
Introduction
Vladimir Karginov is an accomplished inventor based in Ashburn, VA (US). He holds 2 patents that contribute significantly to the fields of biochemistry and toxicology. His work focuses on developing innovative solutions to combat anthrax toxicity and enhance the understanding of translation initiation.
Latest Patents
One of Karginov's notable patents is related to β-Cyclodextrin derivatives. This invention provides low molecular weight compounds that block the pore formed by protective antigen and inhibit anthrax toxin action. The structures of these compounds are derivatives of β-cyclodextrin. Per-substituted alkylamino derivatives displayed inhibitory activity and were protective against anthrax lethal toxin action at low micromolar concentrations. Additionally, the incorporation of one of the alkylamino derivatives into the bilayer lipid membrane with multiple PA channels resulted in a significant decrease in membrane conductance. Thus, this invention also offers methods for protection against anthrax toxicity. Another significant patent is focused on "Vitro suppression as a tool for the investigation of translation initiation." This invention relates to a method for studying translation initiation and identifying potential inhibitors of translation initiation by expressing proteins in the presence of misacylated suppressor tRNAs.
Career Highlights
Karginov has worked with reputable institutions, including the University of Virginia and Innovative Biologics, Inc. His contributions to these organizations have been instrumental in advancing research in his areas of expertise.
Collaborations
Throughout his career, Karginov has collaborated with notable individuals such as Sidney M. Hecht and Andrei V. Karginov. These collaborations have enriched his research and expanded the impact of his inventions.
Conclusion
Vladimir Karginov's innovative work in developing compounds to combat anthrax toxicity and methods for studying translation initiation showcases his significant contributions to science and technology. His patents reflect a commitment to advancing knowledge and providing solutions to critical challenges in biochemistry.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile