Company Filing History:
Years Active: 1999
Title: The Innovative Contributions of Vladimar Korinek
Introduction
Vladimar Korinek is a prominent inventor based in Prague, Czech Republic. He has made significant contributions to the field of cancer research, particularly in understanding the mechanisms of tumor suppression. His work has implications for the treatment and prevention of colorectal cancer.
Latest Patents
Korinek holds a patent titled ".beta.-catenin, TCF-4, and APC interact to prevent cancer." This patent details the interaction between the APC tumor suppressor protein and .beta.-catenin, which is crucial for regulating transcription in colonic epithelium. The findings indicate that the loss of APC function can lead to the early transformation of colonic epithelium, highlighting the importance of .beta.-catenin regulation in cancer development.
Career Highlights
Vladimar Korinek is affiliated with Utrecht University, where he conducts his research. His work has been instrumental in advancing our understanding of the genetic factors involved in colorectal cancer. His research has garnered attention for its potential to influence therapeutic strategies in oncology.
Collaborations
Korinek has collaborated with notable researchers in the field, including Nick Barker and Hans Clevers. These collaborations have further enriched his research and contributed to the advancement of knowledge in cancer biology.
Conclusion
Vladimar Korinek's innovative work in cancer research, particularly through his patent on the interaction of key proteins, underscores his role as a significant inventor in the field. His contributions continue to pave the way for future advancements in cancer treatment and prevention.