Company Filing History:
Years Active: 1983-1988
Title: Inventor Profile: Vivian M. Larson
Introduction: Vivian M. Larson is an influential inventor located in Harleysville, Pennsylvania, with a remarkable portfolio that includes three patents. Her innovative contributions particularly in the field of biotechnology have significantly advanced the understanding and treatment of herpes simplex virus (HSV) infections.
Latest Patents: Among her latest patents is the "Immunogenic Synthetic Peptide Capable of Eliciting Herpes Simplex Virus." This patent describes a synthetic peptide that includes amino acid residues 64 to 77 of the HSV type 1 gB glycoprotein. This invention functions as a synthetic subunit immunogen that stimulates an immune response against HSV1. When chemically conjugated to a protein carrier molecule and administered to test animals, it successfully induces an anti-peptide IgG response, leading to the production of antibodies that neutralize HSV1 infectivity.
Another notable patent is focused on the "Herpes Subunit Vaccine." This innovation presents a refined method for preparing herpes virus subunit antigens suitable for vaccine applications. The process involves treating virus-infected cells with surfactants and varying salt concentrations, followed by a series of chromatographic procedures to isolate glycoproteins while eliminating unwanted components. The patent also includes optional treatments to enhance safety, ensuring that these subunit antigens are viable for vaccine development.
Career Highlights: Vivian M. Larson is currently employed at Merck & Company, Inc., where her significant contributions to herpes virus research have been recognized. Her work is integral to the continuous development of effective vaccine strategies that aim to improve public health outcomes.
Collaborations: Throughout her career, Larson has collaborated with esteemed colleagues in the field, including E Dale Lehman and Emilio A Emini. These collaborations have fostered a productive research environment, leading to advancements in vaccine technology and therapeutic approaches.
Conclusion: Vivian M. Larson's innovative work in the field of herpes virus research exemplifies dedication and advancement in biotechnology. With her patents paving the way for future vaccine developments, Larson continues to be a prominent figure in the scientific community, contributing positively to public health initiatives.