Company Filing History:
Years Active: 2025
Title: Innovator Vivek Nandakumar: Pioneering Thixotropic Biocompatible Gels for Live Cell Observation
Introduction: Vivek Nandakumar, an inventor based in Tempe, AZ, has made significant contributions to the field of biomedical engineering with his innovative developments in biocompatible materials. His work primarily focuses on creating advanced gels for live cell imaging, enhancing research capabilities in cell biology.
Latest Patents: Nandakumar holds a notable patent for a "Thixotropic biocompatible gel for live cell observation in cell computed tomography." This groundbreaking gel is formulated by combining 4-arm polyethylene glycol with fumed silica (PEG-silica). The thixotropic properties of the gel are influenced by the ratio of PEG to silica, allowing for versatile applications in live cell imaging. Through his research, the biocompatibility of the gel has been demonstrated, where cell suspensions in PBS or other mediums are mixed into the PEG-silica gel and incubated for fluorescence live-dead assays. The duration of cell viability within the gels can extend for several days, depending on composition. The unique optical and fluidic properties of the gels enable compatibility with 3D computed tomography, providing a controllable method for cell manipulation by applying and removing pressure on the gels.
Career Highlights: Nandakumar’s affiliation with Arizona State University underscores his commitment to advancing scientific research. He is recognized for his innovative approach to developing materials that facilitate live cell imaging, contributing to a deeper understanding of cellular processes.
Collaborations: Throughout his career, Nandakumar has collaborated with esteemed colleagues, including Deirdre Meldrum and Fengyu Su. These partnerships enhance his research efforts, pushing the boundaries of what is possible in the field of live cell observation technology.
Conclusion: Vivek Nandakumar's work exemplifies the spirit of innovation in the realm of biocompatible materials. His patented thixotropic gel represents a significant advancement for live cell imaging technologies, contributing to both scientific research and practical applications in biomedical engineering. As he continues to develop new technologies, Nandakumar remains a key figure in the ongoing exploration of cellular observation methodologies.