Vito J Mangiardi

Title: Vito J Mangiardi: Innovator in Diagnostic Assays

Introduction

Vito J Mangiardi is a notable inventor based in San Rafael, CA. He has made significant contributions to the field of diagnostic assays, holding a total of 3 patents. His work focuses on improving methods for analyzing serum components, particularly in the context of thyroid hormones and folate levels.

Latest Patents

Mangiardi's latest patents include a "Folate assay with ion exchange resin bound-free separation." This innovative method enhances the competitive binding serum folate assay by effectively separating serum folate bound by a folate-selective protein from free serum folate using an anion exchanger. The use of intermediate base anion exchange resin, particularly those with an aliphatic lattice, is a key feature of this invention. Additionally, he has developed a "Method for the analysis of thyroid hormones." This method involves competitive binding in diagnostic clinical testing for thyroid function, where blood serum is acidified to inactivate binding of thyroid hormone to serum proteins, allowing for a more accurate assessment.

Career Highlights

Mangiardi is currently associated with Bio-Rad Laboratories, Inc., a company renowned for its contributions to the life sciences and clinical diagnostics. His work at Bio-Rad has allowed him to further his research and development in diagnostic technologies.

Collaborations

Throughout his career, Mangiardi has collaborated with esteemed colleagues such as Nathan Lewin and Howard Willner. These partnerships have contributed to the advancement of his innovative projects and the successful development of his patents.

Conclusion

Vito J Mangiardi's contributions to the field of diagnostic assays exemplify his commitment to innovation and improvement in clinical testing methods. His patents reflect a deep understanding of the complexities involved in serum analysis, making significant strides in the medical diagnostics industry.