This inventor holds 2 USPTO granted patents and 3 published patent applications and 2 EPO patents. Top assignees: University of Cape Town, University Of Louisville Research Foundation, Inc.. Active years: 2018-2019.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
2 out of 94 
2 out of 398 
Years Active: 2018-2019
Title: Virna Drucille Leaner: Innovator in Cancer Therapy
Introduction
Virna Drucille Leaner is a notable inventor based in Goodwood, South Africa. He has made significant contributions to the field of cancer therapy through his innovative research and patented inventions. With a total of 2 patents, Leaner is recognized for his work in developing compounds that target cancer cells effectively.
Latest Patents
Leaner’s latest patents include groundbreaking compounds aimed at cancer treatment. The first patent, titled "Substituted benzoxazepine for cancer therapy," describes a compound and methods for inhibiting karyopherin beta 1 activity. This compound, specifically 9-[(1-methylpiperidin-3-yl)methoxy]-4-[(6-methylpyridin-2-yl)methyl]-7-(5-methylthiophen-2-yl)-3,5-dihydro-2H-1,4-benzoxazepine, has shown potential in inhibiting the import of proteins and transcription factors into the nucleus of a cell, thereby exhibiting anti-cancer effects.
The second patent, "Substituted pyrrolo[2,3-b]quinoxalines for cancer therapy," focuses on quinoxaline derivatives that inhibit the nuclear import of proteins such as Kpnα1, AP-1, P65, and NFAT. This inhibition induces apoptosis in cancer cells while leaving non-cancer cells largely unaffected, showcasing the therapeutic potential of these compounds.
Career Highlights
Throughout his career, Leaner has worked with prestigious institutions, including the University of Cape Town and the University of Louisville Research Foundation, Inc. His research has significantly advanced the understanding of cancer treatment methodologies.
Collaborations
Leaner has collaborated with notable colleagues, including Pauline Janet Van Der Watt and John Olaf Trent. These partnerships have contributed to the development of his innovative cancer therapies.
Conclusion
Virna Drucille Leaner stands out as a pioneering inventor in the field of cancer therapy. His patented inventions reflect a commitment to advancing medical science and improving treatment options for cancer patients.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile