Virginia Basso

Title: Innovations in Fungal Infection Treatment by Virginia Basso

Introduction

Virginia Basso is an accomplished inventor based in North Hollywood, CA. She has made significant contributions to the field of medical science, particularly in the treatment of fungal infections. With a total of 3 patents to her name, her work focuses on innovative approaches to combat disseminated fungal diseases.

Latest Patents

Virginia Basso's latest patents include groundbreaking compositions and methods for the treatment of fungal infections. One of her notable inventions involves novel peptide analogs of a θ-defensin. These analogs provide a biphasic effect in treating disseminated fungal disease and/or associated septic shock. They are active at concentrations below those needed to provide a fungicidal effect. The mechanism of action involves initially mobilizing effector cells of the immune system to address the infective organism, followed by the regulation of the immune system to down-regulate the inflammatory response. These θ-defensin analogs are protective at concentrations where naturally occurring θ-defensins have no apparent effect. They include a core set of structural and sequence features not found in native θ-defensins.

Career Highlights

Virginia Basso is affiliated with the University of Southern California, where she continues her research and development efforts. Her work has garnered attention for its potential to improve treatment outcomes for patients suffering from severe fungal infections.

Collaborations

Virginia collaborates with esteemed colleagues, including Michael E Selsted and Dat Q Tran, who contribute to her research endeavors.

Conclusion

Virginia Basso's innovative work in the field of fungal infection treatment showcases her dedication to advancing medical science. Her patents reflect a commitment to developing effective therapies that can significantly impact patient care.