Vincent T Marchesi

Title: The Innovations of Vincent T Marchesi

Introduction

Vincent T Marchesi is a notable inventor based in Guilford, CT (US). He has made significant contributions to the field of immunology, particularly through his work on monoclonal antibodies. With a total of six patents to his name, Marchesi's innovations have had a profound impact on the diagnosis and management of diabetes.

Latest Patents

Among his latest patents are monoclonal antibodies specific for human glycoalbumin. These antibodies target the glycosylated lysine residue at position 525 in glycoalbumin. They are particularly useful as reagents in immunoassays for the specific determination of glycoalbumin in human blood samples. This determination is indicative of the severity of diabetic conditions. The monoclonal antibodies are secreted by hybridomas, which are obtained by fusing a myeloma cell with a lymphocyte from an immunized animal, typically a mouse. The synthetic peptide immunogen used in this process includes an epsilon-amino glucosylated lysine and an adjacent amino acid sequence that corresponds to the peptide sequence of human albumin near lysine 525.

Career Highlights

Vincent T Marchesi has worked with several prominent companies throughout his career, including Molecular Diagnostics, Inc. and Miles Inc. His work has been instrumental in advancing the understanding and treatment of diabetes through innovative diagnostic tools.

Collaborations

Marchesi has collaborated with notable individuals in his field, including William J Knowles and Wallace Haigh. These collaborations have further enhanced the impact of his research and innovations.

Conclusion

Vincent T Marchesi's contributions to the field of immunology, particularly through his patents on monoclonal antibodies, have significantly advanced diabetes diagnostics. His work continues to influence the medical community and improve patient outcomes.