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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 4658022 B1

PDFFull Text
Date of Patent:
Apr. 14, 1987

Filed:

Sep. 27, 1985

Binding of antibody reagents to denatured protein analytes

Applicant:
Inventors:

William J Knowles, Hamden, CT (US);

Vincent T Marchesi, Gulford, CT (US);

Assignee:

Molecular Diagnostics, Inc., West Haven, CT (US);

Attorney:

Sprung Horn Kramer & Woods

Primary Examiner:

Morton Foelak

Assistant Examiner:

Nathan M Nutter

Int. Cl.
CPC ...
A61K / ; G01N / ;
U.S. Cl.
CPC ...
530402 ; 530362 ; 530363 ; 530380 ; 530395 ; 530808 ; 424 88 ; 424 89 ; 435-7 ; 436514 ; 436548 ; 436 86 ; 436 87 ; 436819 ;
Abstract

Binding of a particular protein by an antibody reagent involving denaturation of the protein and use of an antibody reagent specific for binding a linear peptide epitope therein. Denaturation by chemical or physical means effectively exposes or enhances the exposure of the linear peptide epitope for binding by the antibody reagent which is preferably raised against a synthetic peptide immunogen. The technique is particularly useful in performing immunoassays for protein analytes, such as a glycosylated protein, in aqueous test samples.

Find Patent Forward Citations

Knowles, William. (1987). Binding of antibody reagents to denatured protein analytes (U.S. Patent No. 4658022). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4658022

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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