Company Filing History:
Years Active: 2020
Title: Vincent Grenier: Innovator in Photoactivatable Voltage Sensitive Dyes
Introduction
Vincent Grenier is a notable inventor based in Berkeley, California. He has made significant contributions to the field of biochemistry through his innovative work on photoactivatable voltage sensitive dyes. His research focuses on compounds and methods that are essential for determining transmembrane potential, monitoring changes in transmembrane potential, and drug screening.
Latest Patents
Vincent Grenier holds a patent for his invention titled "Photoactivatable voltage sensitive dyes." This patent describes compounds with a specific structure represented by the formula: E-M-A-C*. In this formula, A is a fluorophore selected from various categories, including xanthenes, coumarins, cyanines, bimanes, and difluoroboradizaindacenes, which are charged at physiological pH. M represents a molecular wire, while E is a hydrophobic moiety. The compounds are designed to facilitate photo-induced, intramolecular electron transfer that quenches the fluorescence of A in response to voltage conditions. These compounds are membrane-impermeant and are oriented within the cell membrane to localize the charged moiety at the outer leaflet of the lipid bilayer.
Career Highlights
Vincent Grenier's career is marked by his dedication to advancing scientific knowledge in the field of biochemistry. His innovative approach to developing voltage-sensitive dyes has opened new avenues for research and applications in drug screening and cellular monitoring.
Collaborations
Vincent collaborates with Evan Walker Miller, contributing to the advancement of their shared research interests.
Conclusion
Vincent Grenier's work on photoactivatable voltage sensitive dyes exemplifies the intersection of innovation and practical application in biochemistry. His contributions are paving the way for future advancements in the field.