Location History:
- Maharashtra, IN (2010)
- Pune, IN (2013)
Company Filing History:
Years Active: 2010-2013
Title: The Innovative Contributions of Vilas Bhiku Chavan
Introduction
Vilas Bhiku Chavan is a notable inventor based in Pune, India. He has made significant contributions to the field of chemistry, particularly in the synthesis of bioactive compounds and lactic acid derivatives. With a total of 2 patents to his name, Chavan's work has implications in pharmaceuticals and industrial applications.
Latest Patents
Chavan's latest patents include a process for the preparation of β-amino alcohol and a commercially viable method for producing L-(+)-lactic acid. The first patent details a high-yielding enantioselective synthesis of the bioactive (S)—N-(5-chlorothiophene-2-sulfonyl)-β,β-diethylalaniol, which acts as a Notch-1-sparing γ-secretase inhibitor metabolite. This synthesis starts from readily available 3-pentanone and involves key steps such as proline-catalyzed α-aminooxylation and α-amination of aldehyde, achieving an overall yield of 50-75% and 90-99% enantiomeric excess. The second patent outlines a process for preparing highly pure and optically active L-(+)-lactic acid from sugar cane juice fermentation broth and methanol, utilizing a continuous counter-current trickle phase approach. This method results in a product that has various applications in food, pharmaceuticals, and biodegradable polymers.
Career Highlights
Chavan is affiliated with the Council of Scientific & Industrial Research, where he continues to innovate and contribute to scientific advancements. His work has garnered attention for its practical applications and potential impact on various industries.
Collaborations
Chavan has collaborated with notable colleagues such as Prashant Purushottam Barve and Bhaskar Dattatreya Kulkarni, enhancing the scope and depth of his research endeavors.
Conclusion
Vilas Bhiku Chavan's contributions to the field of chemistry through his innovative patents demonstrate his commitment to advancing scientific knowledge and practical applications. His work not only benefits the pharmaceutical industry but also paves the way for sustainable practices in various sectors.