Victor L Perez

Title: Victor L Perez: Innovator in HIV Research

Introduction

Victor L Perez is a notable inventor based in Rio Piedras, Puerto Rico. He has made significant contributions to the field of HIV research, particularly through his innovative patent that addresses chronic HIV-1 infection. His work is crucial in understanding the complexities of HIV and its effects on human health.

Latest Patents

Victor L Perez holds a patent for a unique physiologic model of chronic human immunodeficiency virus type-1 (HIV-1) infection. The patent, titled "CD4.sup.+, latently HIV-1-infected hematopoietic progenitor cells," describes a chronically infected promyelocyte cell line that harbors a single integrated provirus. This model is distinct as it maintains CD4.sup.+ expression under normal culture conditions, with less than 10% of the cells expressing HIV-1 proteins. Upon treatment with tumor necrosis factor-alpha (TNF-.alpha.), the cell line shows a dramatic increase in HIV-1 expression, with over 95% of the cells becoming HIV-1.sup.+. This innovative approach provides insights into the mechanisms of viral activation and CD4 down-modulation.

Career Highlights

Victor L Perez is associated with the United States of America as represented by the Department of Health. His work has been instrumental in advancing the understanding of HIV-1 infection and its implications for treatment and research.

Collaborations

Victor has collaborated with notable colleagues such as Salvatore T Butera and Thomas M Folks. Their combined expertise contributes to the ongoing research and development in the field of HIV.

Conclusion

Victor L Perez is a pioneering inventor whose work in HIV research has the potential to impact treatment strategies significantly. His innovative patent reflects a deep understanding of viral mechanisms and offers a valuable model for future studies.