Company Filing History:
Years Active: 1980-1991
Title: Verlan H VanRheenen: Innovator in Corticoid Chemistry
Introduction
Verlan H VanRheenen is a notable inventor based in Portage, MI (US), recognized for his significant contributions to the field of corticoid chemistry. With a total of 12 patents to his name, he has made substantial advancements in the production and transformation of steroid compounds.
Latest Patents
One of his latest patents is the 16.alpha.-methylation process. This innovative process involves the production of a .DELTA..sup.17(20)-steroid by starting with a 16-unsaturated corticoid and contacting it with a methylating agent in the presence of a copper catalyst and a silylating agent. Additionally, the 16.alpha.-methylation process allows for the transformation of C.sub.16-unsaturated corticoids into the corresponding 16.alpha.-methyl-17.alpha.-hydroxy corticoids using a .DELTA..sup.17 (.sup.20)-20-silyl ether.
Career Highlights
Verlan H VanRheenen has spent a significant portion of his career at The Upjohn Company, where he has been instrumental in developing innovative processes that enhance the production of steroid compounds. His work has not only contributed to the scientific community but has also had practical applications in pharmaceuticals.
Collaborations
Throughout his career, VanRheenen has collaborated with esteemed colleagues such as Joel E Huber and Edward J Hessler. These collaborations have fostered an environment of innovation and have led to the successful development of various patented processes.
Conclusion
Verlan H VanRheenen's contributions to corticoid chemistry through his patents and collaborations highlight his role as a significant inventor in the field. His work continues to influence the production of steroid compounds, showcasing the importance of innovation in scientific research.