Kansas City, MO, United States of America

Venkatesh Swaminathan


Average Co-Inventor Count = 4.0

ph-index = 1

Forward Citations = 2(Granted Patents)


Location History:

  • Kolkata, IN (2008)
  • Kansas City, MO (US) (2010)

Company Filing History:


Years Active: 2008-2010

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2 patents (USPTO):Explore Patents

Title: Innovations by Venkatesh Swaminathan

Introduction

Venkatesh Swaminathan is an accomplished inventor based in Kansas City, MO (US). He has made significant contributions to the field of biochemistry, particularly in the area of histone acetyltransferases and their implications in gene regulation and cancer treatment. With a total of 2 patents, his work is paving the way for new therapeutic approaches.

Latest Patents

Swaminathan's latest patents include innovative compounds that serve as modulators of histone acetyltransferases. The first patent focuses on the use of specific benzoic acid and benzamide compounds as inhibitors and activators of these enzymes, which play a crucial role in gene expression and cancer. This invention holds promise for treating diseases caused by defects in gene regulation, predominantly cancer.

The second patent describes the purification of polyisoprenylated benzophenones from fruit rinds and their evaluation as inhibitors for histone acetyltransferases p300 and PCAF. The findings indicate that these compounds are potent inhibitors, significantly repressing p300 HAT-dependent transcriptional activation. This suggests their potential as biological switching molecules for evaluating the roles of p300 and PCAF in cellular functions, as well as their utility in developing new anticancer drugs.

Career Highlights

Venkatesh Swaminathan is affiliated with the Jawaharlal Nehru Centre for Advanced Scientific Research, where he conducts his research. His work has garnered attention for its innovative approach to understanding and manipulating gene regulation mechanisms.

Collaborations

Swaminathan collaborates with notable colleagues, including Karanam Balasubramanyam and Tapas Kumar Kundu. Their combined expertise enhances the research output and fosters a collaborative environment for scientific discovery.

Conclusion

Venkatesh Swaminathan's contributions to the field of biochemistry through his patents on histone acetyltransferases highlight the potential for new cancer therapies. His innovative work continues to inspire advancements in gene regulation research.

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