Veena M Vasandani

Title: Veena M Vasandani: Innovator in Recombinant Protein Technology

Introduction

Veena M Vasandani is a notable inventor based in Rockville, MD (US). He has made significant contributions to the field of biotechnology, particularly in the development of recombinant proteins with therapeutic applications. With a total of 2 patents, his work focuses on innovative methods for producing cytotoxic ribonucleolytic proteins.

Latest Patents

Vasandani's latest patents include a mutant form of a cytotoxic ribonucleolytic protein that allows for production by recombinant methods. This invention provides recombinant Onc (rOnc) compositions and methods. The recombinant Onc proteins feature an amino terminal methionine, which facilitates recombinant production in bacterial host cells. Cleaving the amino terminal methionine reveals the amino terminal glutamine of the polypeptide, which is crucial for its functionality. The Onc polypeptide possesses an amino terminal glutamine, and cyclization of this residue to a pyroglutamyl form results in rOnc polypeptides and proteins that exhibit anti-cancer and anti-viral activity.

Career Highlights

Vasandani is affiliated with the National Institutes of Health, a component of the US Department of Health & Human Services. His work at this prestigious institution underscores his commitment to advancing medical research and therapeutic development.

Collaborations

Some of his notable coworkers include Richard J Youle and Yon-Neng Wu, who have collaborated with him on various research projects.

Conclusion

Veena M Vasandani's innovative work in recombinant protein technology has the potential to significantly impact the fields of cancer and viral therapies. His contributions reflect a dedication to scientific advancement and the pursuit of effective medical solutions.