Valérie Legrand

Title: Valérie Legrand: Innovator in Adenoviral Research

Introduction

Valérie Legrand is a prominent inventor based in Strasbourg, France. He has made significant contributions to the field of adenoviral research, holding a total of 2 patents. His work focuses on modifying adenovirus fibers to enhance their therapeutic applications.

Latest Patents

Legrand's latest patents include "Modified adenovirus fiber and uses" and "Modified adenoviral fiber and target adenoviruses." The first patent concerns an adenovirus fiber modified by mutation of one or several residues in a specific region. This invention includes viral particles or pseudo-particles that comprise such a fiber and their various uses. The second patent relates to an adenovirus fiber modified by the mutation of one or more residues directed towards the natural cell receptor in the three-dimensional structure of the adenovirus. This invention also encompasses a DNA fragment, an expression vector, and a cell line expressing the modified fiber, along with their therapeutic applications and corresponding pharmaceutical compositions.

Career Highlights

Throughout his career, Valérie Legrand has worked with notable companies, including Transgene and Transgene S.A. His innovative research has positioned him as a key figure in the field of biotechnology, particularly in the development of adenoviral therapies.

Collaborations

Legrand has collaborated with esteemed colleagues such as Majid Mehtali and Pierre Boulanger. These partnerships have furthered his research and contributed to advancements in adenoviral applications.

Conclusion

Valérie Legrand's work in adenoviral research exemplifies the impact of innovation in biotechnology. His patents and collaborations highlight his commitment to advancing therapeutic solutions.