Valerie Goss

Title: Valerie Goss: Innovator in Protein Phosphorylation Detection

Introduction

Valerie Goss is a prominent inventor based in Seabrook, NH (US), known for her significant contributions to the field of protein phosphorylation detection. With a total of three patents to her name, she has made remarkable advancements in understanding signaling pathways in various biological contexts.

Latest Patents

Her latest patents include groundbreaking inventions such as reagents for the detection of protein phosphorylation in signaling pathways. This invention discloses novel phosphorylation sites identified in signal transduction proteins and pathways. It provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites and proteins. The methods of using these reagents are also outlined. Among the phosphorylation sites identified are those occurring in various protein types, including adaptor/scaffold proteins, adhesion/extracellular matrix proteins, apoptosis proteins, calcium binding proteins, and many others. Another notable patent focuses on tyrosine phosphorylation sites, disclosing 482 novel phosphorylation sites identified in carcinoma and/or leukemia. This includes peptides comprising a phosphorylation site of the invention, antibodies that specifically bind to these novel phosphorylation sites, and their diagnostic and therapeutic uses.

Career Highlights

Valerie Goss is currently associated with Cell Signaling Technology, Inc., where she continues to innovate and contribute to the field of protein research. Her work has been instrumental in advancing the understanding of protein functions and their implications in health and disease.

Collaborations

She has collaborated with notable coworkers such as Ting-Lei Gu and Albrecht Moritz, further enhancing the impact of her research through teamwork and shared expertise.

Conclusion

Valerie Goss stands out as a leading inventor in the realm of protein phosphorylation detection, with her innovative patents paving the way for advancements in biomedical research. Her contributions are vital for the ongoing exploration of protein functions and their roles in various diseases.