Company Filing History:
Years Active: 2007
Title: Valerie Gail Montana: Innovator in Nuclear Receptor Research
Introduction
Valerie Gail Montana, based in Durham, North Carolina, is an accomplished inventor known for her significant contributions to the field of nuclear receptor research. She holds a patent that focuses on a crystallized glucocorticoid receptor ligand binding domain polypeptide, showcasing her innovative approach to modifying test nuclear receptor polypeptides.
Latest Patents
Valerie's notable patent, titled "Crystallized glucocorticoid receptor ligand binding domain polypeptide and screening methods employing same," presents a groundbreaking method for altering a test nuclear receptor (NR) polypeptide. The patented method involves meticulously aligning a test NR polypeptide sequence with established reference NR polypeptide sequences that have existing X-ray structures. By constructing a three-dimensional model based on these reference sequences, Valerie’s method enables researchers to examine and identify characteristic differences, facilitating targeted modifications through amino acid mutation.
Career Highlights
Valerie has made remarkable strides in her career, and her affiliation with SmithKline Beecham Corporation has allowed her to pursue her innovative research. Her work has not only enhanced the understanding of nuclear receptors but has also opened new avenues for therapeutic development in related fields.
Collaborations
Throughout her career, Valerie has collaborated with several notable colleagues, including Christopher J. Apolito and Randy K. Bledsoe. Together, they have contributed to advancing research and innovation, further establishing Valerie's reputation as a leading figure in her field.
Conclusion
Valerie Gail Montana stands out as a visionary inventor in the realm of nuclear receptor research. Her patent on modified test NR polypeptides exemplifies her commitment to advancing scientific knowledge and developing practical applications for modern medicine. As she continues her work at SmithKline Beecham Corporation, Valerie remains an inspiring figure for aspiring inventors and researchers alike.