Company Filing History:
Years Active: 2012-2016
Title: Ute Lange: Innovator in Hemostatic System Modifications
Introduction
Ute Lange is a notable inventor based in Kahla, Germany. She has made significant contributions to the field of biochemistry, particularly in the area of hemostatic systems. With a total of 2 patents, her work focuses on innovative methods for modifying peptidases and determining clotting activity in blood samples.
Latest Patents
One of Ute Lange's latest patents is titled "Polymer-coupled peptidases." This invention presents a straightforward process for modifying the specificity of a peptidase within the hemostatic system. By coupling polymers to the peptidase, it loses its reactivity in the hemostatic system while retaining the ability to interact with specific inhibitors, effectors, and substrates. The invention also encompasses processes for detecting or quantitatively determining inhibitors of the peptidase in bodily fluids or other samples. Furthermore, it provides methods for neutralizing or removing these inhibitors from liquids. Additionally, the invention allows for the use of a polymer-coupled peptidase as a drug and introduces a device that utilizes such a peptidase to eliminate inhibitors from samples or the bloodstream of patients.
Another significant patent is the "Method for determining the total clotting activity of a blood or plasma sample." This invention outlines a method that involves adding a highly specific, reversible thrombin inhibitor to a blood or plasma sample in a defined amount. The clotting of the sample is then induced, and after a specified period, the consumed amount of the thrombin inhibitor is determined. This method is accompanied by a kit designed to provide information about the coagulation state of a blood sample.
Career Highlights
Throughout her career, Ute Lange has worked with several prominent companies, including Senova Gesellschaft für Biowissenschaft und Technik mbH and Jenaffin GmbH. Her experience in these organizations has contributed to her expertise in the field of biochemistry and hemostatic systems.
Collaborations
Ute Lange has collaborated with notable colleagues, including Elke Bucha and Hans-Jürgen Kolde. These partnerships have likely enhanced her research and development efforts in her innovative projects.
Conclusion
Ute Lange's contributions to the field of biochemistry, particularly in the modification of hemostatic systems, showcase her innovative