Company Filing History:
Years Active: 1993-1994
Title: Usha Josyula: Innovator in Pharmaceutical Chemistry
Introduction
Usha Josyula is a prominent inventor based in Ann Arbor, MI (US). She has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of novel compounds for medical applications. With a total of 2 patents, her work focuses on innovative solutions for treating various autoimmune diseases.
Latest Patents
Usha Josyula's latest patents include the invention of 9-Substituted-8-halo or -8-hydroxy-9-deazaguanines as inhibitors of purine nucleoside phosphorylase (PNP). These compounds are designed to be selectively cytotoxic to T-cells while sparing B-cells in the presence of 2'-deoxyguanosine. This unique property makes them valuable for treating conditions such as autoimmune diseases, gout, psoriasis, and transplant rejection. The patents also encompass certain novel intermediates that contribute to the efficacy of these compounds.
Career Highlights
Usha Josyula is currently associated with Warner-Lambert Company, where she continues to advance her research and development efforts. Her work has garnered attention for its potential impact on therapeutic strategies in immunology and oncology.
Collaborations
Usha collaborates with Jagadish C Sircar, enhancing her research through shared expertise and innovative ideas.
Conclusion
Usha Josyula's contributions to pharmaceutical chemistry exemplify the importance of innovation in developing new treatments for complex diseases. Her patents reflect a commitment to advancing medical science and improving patient outcomes.