Uri Ben-david

Title: Uri Ben-David: Innovator in CRISPR-Based Therapeutics

Introduction

Uri Ben-David is a prominent inventor based in Cambridge, MA (US). He has made significant contributions to the field of genetic engineering, particularly in the development of CRISPR-based systems and therapies. His innovative work focuses on the rational design of these systems, which has the potential to revolutionize therapeutic approaches in medicine.

Latest Patents

Uri Ben-David holds a patent for his invention titled "DNA damage response signature guided rational design of CRISPR-based systems and therapies." This patent describes methods to design CRISPR-Cas system-based therapeutics by utilizing the expression of a DNA-damage response signature in cells. The methods involve screening various CRISPR-Cas systems in a test cell population, modifying target sequences, and selecting systems that do not trigger a DNA-damage response signature. This innovative approach aims to enhance the efficacy and safety of CRISPR-based therapies.

Career Highlights

Throughout his career, Uri Ben-David has worked with esteemed organizations such as the Broad Institute, Inc. and Dana-Farber Cancer Institute Inc. His experience in these leading research institutions has allowed him to collaborate with some of the brightest minds in the field of cancer research and genetic engineering.

Collaborations

Uri has collaborated with notable colleagues, including Todd R. Golub and Rameen Beroukhim. These partnerships have contributed to advancing research in CRISPR technology and its applications in therapeutic settings.

Conclusion

Uri Ben-David is a key figure in the innovation of CRISPR-based therapeutics, with a focus on enhancing the design and application of these systems. His contributions to the field are paving the way for future advancements in genetic engineering and medicine.