This inventor holds 1 USPTO granted patent. Top assignee: Scios Inc.. Active years: 2016.
Company Filing History:
Years Active: 2016
Title: Urban A Kieman: Innovator in Biological Fluid Sampling
Introduction
Urban A Kieman is a notable inventor based in Chandler, AZ (US). He has made significant contributions to the field of biological fluid sampling, particularly in the area of natriuretic peptides. His innovative approach has led to the development of a unique method and composition that enhances the accuracy of peptide sampling.
Latest Patents
Urban A Kieman holds a patent for a "Method, composition and device for sampling natriuretic peptides in a biological fluid." This patent discloses a composition that synergistically prevents proteolysis or modification of peptides in sampled biological fluids. The composition utilizes sulfonyl fluoride family protease inhibitors at high concentrations, combined with at least one additional protease inhibitor of a different type, preferably a broad-spectrum protease inhibitor, and a chelator. A preferred embodiment of this invention employs AEBSF at 10 mM, Benzamidine at 20 mM, and EDTA as the chelator. The disclosed composition can be combined with other protease inhibitors to further modulate its specificity, particularly targeting acidic proteases. Additional protease inhibitors, reducing agents, stabilizers, and buffering agents may also be included in devices for sampling or testing biological fluids for levels of peptides of interest.
Career Highlights
Urban A Kieman is associated with Scios Inc., where he has been instrumental in advancing research and development in his field. His work has focused on improving methods for sampling and testing biological fluids, which is crucial for accurate medical diagnostics.
Collaborations
He has collaborated with notable colleagues, including Ute Schellenberger and Randall W Nelson, contributing to a dynamic research environment that fosters innovation and development.
Conclusion
Urban A Kieman's contributions to the field of biological fluid sampling exemplify the impact of innovative thinking in medical research. His patented methods and compositions are paving the way for more accurate testing and diagnostics in healthcare.