Company Filing History:
Years Active: 1997-2000
Title: Umberto Pace: Innovator in RNA Technology
Introduction
Umberto Pace is a notable inventor based in Riverdale, NY (US). He has made significant contributions to the field of RNA technology, holding 2 patents that focus on modified external guide sequence molecules. His work aims to enhance the treatment of viral infections, particularly hepatitis B.
Latest Patents
Pace's latest patents include innovative approaches to RNA cleavage. The first patent involves the construction of modified external guide sequence (EGS) molecules that mediate the cleavage of specific target RNAs. These molecules are designed to bind specifically to target RNA and promote RNAse P-mediated cleavage while exhibiting enhanced nuclease resistance. The modifications made to specific regions of these molecules ensure improved stability without compromising RNAse P activity. The second patent similarly focuses on EGS-mediated inactivation of target RNA, emphasizing the potential for treating hepatitis B viral infections through these advanced molecular techniques.
Career Highlights
Throughout his career, Umberto Pace has worked with esteemed institutions such as Yale University and Innovir Laboratories, Inc. His experience in these organizations has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research in RNA technology.
Collaborations
Pace has collaborated with notable colleagues, including Shaji T George and Michael Ma. These partnerships have further enriched his research and development efforts in the realm of RNA-based therapies.
Conclusion
Umberto Pace's innovative work in RNA technology and his contributions to the treatment of viral infections highlight his importance as an inventor. His patents reflect a commitment to advancing medical science and improving patient outcomes.