This inventor holds 2 USPTO granted patents. Top assignee: Hoechst Aktiengesellschaft. Active years: 1995-1998.
Location History:
- Niedernhausen, DE (1995)
- Diez, DE (1998)
Company Filing History:
Years Active: 1995-1998
Title: Ulrich Holst: Innovator in Recombinant Processes
Introduction
Ulrich Holst is a notable inventor based in Niedernhausen, Germany. He has made significant contributions to the field of biotechnology, particularly in the development of recombinant processes. With a total of 2 patents, his work has advanced the understanding and application of enzymatic processes.
Latest Patents
Holst's latest patents include an "Induction-free process for the recombinant preparation of glutarylamidase" and an "Improved, induction-free process for the recombinant preparation of glutarylamidase." These inventions focus on a recombinant process for preparing glutarylamidase (GA), where the GA gene is expressed constitutively from an expression vector. In certain embodiments, the promoter used for this expression is a trc promoter or a trc-equivalent promoter that does not have any repressor or has a non-functional repressor. Additionally, he has developed a process for the selective deactivation of esterases and catalases in Trigonopsis variabilis cells. This process involves microwave heating of intact cells to temperatures between 60°C and 68°C for 20 to 40 seconds, selectively deactivating esterases and catalases while retaining the activity of D-amino acid oxidase.
Career Highlights
Holst is associated with Hoechst Aktiengesellschaft, a prominent company in the pharmaceutical and chemical sectors. His work at Hoechst has allowed him to explore innovative solutions in biotechnology, contributing to the company's reputation for excellence in research and development.
Collaborations
Throughout his career, Holst has collaborated with esteemed colleagues such as Werner Aretz and Klaus Peter Koller. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and advancements in their respective fields.
Conclusion
Ulrich Holst's contributions to recombinant processes and enzymatic applications highlight his role as an influential inventor in biotechnology. His innovative patents and collaborations continue to impact the industry positively.