Company Filing History:
1 out of 1,373 
1 out of 832,812 Years Active: 1998-2005
Title: Tucker Collins: Innovator in Atherosclerosis Research
Introduction
Tucker Collins is a notable inventor based in Cohasset, MA (US). He has made significant contributions to the field of medical research, particularly in understanding and treating atherosclerosis. With a total of 2 patents, Collins has developed innovative methods that have the potential to impact patient care and treatment outcomes.
Latest Patents
Collins' latest patents include "Inhibition of Egr-1 expression by ppar-gamma agonists and related compositions and methods." This invention provides methods for determining whether an agent increases PPAR-γ-mediated inhibition of Egr-1 expression. It also offers methods for inhibiting the onset of atherosclerosis in transplanted organs. Furthermore, this invention outlines numerous methods for treating disorders and inhibiting the onset of disorder-related complications using PPAR-γ agonists. Additionally, it provides related methods for inhibiting cancer metastasis, treating and preventing heart attacks, and addressing burn and crush injuries.
Another significant patent is "Mononuclear leukocyte directed endothelial adhesion molecule associated." This invention relates to novel endothelial cell-leukocyte adhesion molecules designated ATHERO-ELAM. ATHERO-ELAM molecules are expressed on cultured endothelial cells stimulated with bacterial LPS and selectively mediate the binding of monocytes to these cells. Monoclonal antibodies specific for ATHERO-ELAM bind to vascular endothelial cells involved in early atherosclerotic lesions, but not to those from uninvolved arterial tissue. This invention may be used in identifying early atherosclerotic lesions and in treating and preventing atherosclerosis.
Career Highlights
Throughout his career, Collins has worked with reputable institutions, including The Brigham and Women's Hospital, Inc. His research has focused on critical areas that address cardiovascular health and related disorders.
Collaborations
Collins has collaborated with esteemed colleagues such as David J Pinsky and Michael A Gimbrone, Jr. These partnerships have furthered his research and contributed to the advancements in his field.
Conclusion
Tucker Collins is a distinguished inventor whose work in atherosclerosis research has led to valuable patents and innovative methods for treatment. His contributions continue to influence the medical community and improve patient outcomes.