Tuah R Jenta

Title: Innovations of Tuah R Jenta in Anti-HIV Research

Introduction

Tuah R Jenta is an accomplished inventor based in Chicago, IL (US). He has made significant contributions to the field of pharmaceutical sciences, particularly in the isolation of anti-HIV agents. His innovative work has the potential to impact the treatment of HIV, showcasing the importance of research in combating viral infections.

Latest Patents

Tuah R Jenta holds a patent for a scalable method for the isolation of anti-HIV agents from tropical plants. This patent details an efficient and scalable method for isolating costatolide, an HIV-1-specific nonnucleoside reverse transcriptase inhibitor (NNRTI), from the latex of Calophyllum plants. The method achieved an overall yield of 10.6% of costatolide with a purity of 96%. This was accomplished through repetitive recrystallization of the latex after removing oily material with hexane. Additionally, soulattrolide, another HIV-1 NNRTI, was also isolated and characterized. The in vitro anti-HIV activities of both compounds were confirmed, indicating their potential for therapeutic use.

Career Highlights

Tuah R Jenta is associated with Sarawak Medichem Pharmaceuticals, Inc., where he continues to advance his research in pharmaceutical innovations. His work emphasizes the importance of utilizing natural sources for drug development, which can lead to cost-effective solutions for HIV treatment.

Collaborations

Tuah has collaborated with notable colleagues, including Yuh-Meei Lin and Herbert M Anderson. These collaborations have contributed to the successful development and characterization of his patented methods and compounds.

Conclusion

Tuah R Jenta's innovative research in the isolation of anti-HIV agents demonstrates the potential for natural compounds in pharmaceutical applications. His contributions are vital in the ongoing fight against HIV, highlighting the importance of continued research and innovation in this field.