Location History:
- Miaoli County, TW (2019)
- Zhunan Township, TW (2024)
Company Filing History:
Years Active: 2019-2024
Title: Tsung-Hsien Chuang: Innovator in Cancer Immunotherapy
Introduction
Tsung-Hsien Chuang is a prominent inventor based in Miaoli County, Taiwan. He has made significant contributions to the field of cancer immunotherapy, focusing on innovative methods to enhance immune responses against tumors. With a total of 3 patents, his work is paving the way for new therapeutic strategies in oncology.
Latest Patents
One of his latest patents is titled "CpG-oligodeoxynucleotide compounds in combination with immune modulators for cancer immunotherapy." This invention discloses a combinational therapy aimed at enhancing the efficacy of immune checkpoint blockade for tumors characterized by an immune suppressive microenvironment. The therapy involves the use of immune checkpoint inhibitors alongside CpG-oligodeoxynucleotides to treat cancer effectively.
Another notable patent is the "Method of stimulating TLR9-activated immune response." This method focuses on enhancing the TLR9-activated immune response to an antigen. TLR9 serves as the cellular receptor for CpG-ODN, and the developed CpG-ODN has shown low activity in rabbit TLR9. The method demonstrates potent immunostimulatory activity by administering an effective amount of an immunogenic composition that includes an antigen and a CpG-ODN with GACGTT or AACGTT motifs, leading to a robust antibody response in rabbits.
Career Highlights
Tsung-Hsien Chuang is affiliated with the National Health Research Institutes, where he conducts his research and development activities. His work is instrumental in advancing the understanding and treatment of cancer through innovative immunotherapeutic approaches.
Collaborations
He collaborates with notable colleagues, including Chao-Yang Lai and Yi-Ling Liu, to further enhance the impact of his research in the field of immunotherapy.
Conclusion
Tsung-Hsien Chuang's contributions to cancer immunotherapy through his innovative patents highlight his role as a leading inventor in the field. His work continues to inspire advancements in therapeutic strategies for cancer treatment.